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Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 433-444 doi: 10.1007/s11705-014-1454-6

Abstract: The aggregation of amyloid -protein (A ) is tightly linked to the pathogenesis of Alzheimer’s diseaseMM/PBSA analysis further revealed that different peptide inhibitors have different modes of interaction

Keywords： Alzheimer’s disease     amyloid β-protein     peptide inhibitors     protein-protein interaction     molecular    

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Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction

Hong LI,Ziding ZHANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2,   Pages 102-112 doi: 10.15302/J-FASE-2016100

Abstract: great opportunity to explore plant–pathogen interactions from a systems perspective and studies on protein–protein

Keywords： plant–pathogen interactions     systems biology     omics     plant immunity     protein–protein interaction     network    

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Molecular simulation of the interaction mechanism between CodY protein and DNA in

Linchen Yuan, Hao Wu, Yue Zhao, Xiaoyu Qin, Yanni Li

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 1,   Pages 133-139 doi: 10.1007/s11705-018-1737-4

Abstract: In order to study the mechanism of interaction between CodY and its target DNA, molecular docking and

Keywords： CodY     DNA     molecular docking     molecular dynamics    

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Overlap maximum matching ratio (OMMR): a new measure to evaluate overlaps of essential modules

Xiao-xia ZHANG,Qiang-hua XIAO,Bin LI,Sai HU,Hui-jun XIONG,Bi-hai ZHAO

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 4,   Pages 293-300 doi: 10.1631/FITEE.1400282

Abstract: purification, and mass spectrometry high-throughput proteomic techniques supplies a large amount of protein-proteininteraction data, which make it possible to predict overlapping complexes through computational methodsScholars pay more attention to the evaluation of protein complexes.comprehensive comparison of serveral overlapping complexes prediction approaches, using three yeast protein-proteininteraction (PPI) networks.

Keywords： Protein-protein interaction network     Essential protein modules     Overlap     Overlap maximum matching ratio    

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The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases

Yuan CHEN, Qi TIAN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 70-76 doi: 10.1007/s11684-011-0119-9

Abstract:

Protein kinase C epsilon (PKC ?) is one of major isoforms in novel PKC family.

Keywords： protein kinase C ?     signal transduction     neurogenic disease    

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Wheat gluten protein and its impacts on wheat processing quality

Wujun MA, Zitong YU, Maoyun SHE, Yun ZHAO, Shahidul ISLAM

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 3,   Pages 279-287 doi: 10.15302/J-FASE-2019267

Abstract: Wheat grain protein is divided into gluten and non-gluten fractions and the wheat processing qualityBased on the SDS-extractability, grain protein is divided into SDS-unextractable polymeric protein (UPP) and SDS-extractable polymeric protein.

Keywords： wheat gluten     consensus motifs     disulfide bonds     SDS-unextractable polymeric protein     glutenins     gliadins     processing quality     storage protein    

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Construction of sustainable, colored and multifunctional protein silk fabric using biomass riboflavin

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 8,   Pages 1131-1139 doi: 10.1007/s11705-023-2321-0

Abstract: modification of silk fabric by impregnation with riboflavin sodium phosphate was proposed, such that protein

Keywords： biomass     riboflavin sodium phosphate     silk protein     multifunctional modification     flame retardant    

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Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:

Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 319-323 doi: 10.1007/s11684-017-0553-4

Abstract:

Antithrombin and protein C are two crucial members in the anticoagulant system and play importantCoagulation tests revealed that the patient presented type I antithrombin deficiency combined with decreased proteinThis study demonstrates that the combination of antithrombin deficiency and decreased protein C activity

Keywords： antithrombin deficiency     protein C activity     mutation     variant     venous thromboembolism     anticoagulants    

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Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology and protein

Baicheng HUANG, Kegong TIAN

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2,   Pages 218-226 doi: 10.15302/J-FASE-2020324

Abstract: The relationship of spatial structural characteristics of the spike protein, a protein that is critical

Keywords： bat     coronavirus     evolution     host receptor     spike protein     transmission    

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Elevated C-reactive protein levels predict worsening prognosis in Chinese patients with first-onset stroke

Jiangtao YAN, Rutai HUI, Daowen WANG

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 30-35 doi: 10.1007/s11684-009-0005-x

Abstract: The role of high sensitivity C-reactive protein (hsCRP) in predicting prognosis after stroke in the Asian

Keywords： C-reactive protein     inflammation     stroke    

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Recombinant protein diannexin prevents preeclampsia-like symptoms in a pregnant mouse model via reducing

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 919-931 doi: 10.1007/s11684-021-0918-6

Abstract: This study describes a strategy to prevent PE by reducing MP release using the recombinant protein, diannexin

Keywords： preeclampsia     recombinant protein diannexin     microparticle     NLRP3 inflammasome     phosphatidylserin    

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Investigation of hydrolysis conditions and properties on protein hydrolysates from flatfish skin

Hua ZHANG, Hongji ZHU, Shipeng WANG, Weihua WANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 3,   Pages 303-311 doi: 10.1007/s11705-013-1341-6

Abstract: based on Box-Behnken design, was used to optimize the enzymatic hydrolysis conditions of flatfish skin protein

Keywords： flatfish skin     protein hydrolysates     metal chelating activity     reducing power    

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Correlativity study between expression of DNA double-strand break repair protein and radiosensitivity

Liang ZHUANG, Shiying YU, Xiaoyuan HUANG, Yang CAO, Huihua XIONG

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 26-29 doi: 10.1007/s11684-009-0008-7

Abstract: clone formation assay, and western blot was applied to detect the expressions of Ku80, DNA-PKcs and ATM proteinThe correlativity of protein expression with SF2 value was analyzed by Pearson linear correlation analysisWe found that the expression of same protein in different cell lines and the expression of three proteinsThese findings suggest that the expression level of DNA-PKcs protein can be an indicator for predicting

Keywords： Ku80     DNA-PK(cs)-binding protein     human     ataxia telangiectasia mutated protein     tumor cell lines     radiosensitivity    

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Protein phosphatase 2A, a key player in Alzheimer’s disease

Rong LIU, Qing TIAN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 8-12 doi: 10.1007/s11684-009-0017-6

Abstract: Protein phosphatase 2A (PP2A) is the predominant serine/threonine phosphatase in eukaryotic cells.is suggested to be involved in neurofibrillary tangle (NFT) formation, disturbed amyloid precursor protein

Keywords： protein phosphatase 2A     Alzheimer’s disease     holoenzyme composition     protein phosphatase 2A inhibitors     Leu309    

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Molecular mechanisms of leukemia-associated protein degradation

Ying-Li WU, Guo-Qiang CHEN, Hu-Chen ZHOU,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 363-370 doi: 10.1007/s11684-010-0210-7

Abstract: The interaction between chemistry and biology not only provides new insight into the understanding ofas retinoic acid receptor-alpha (RARα), acute myeloid leukemia 1 (AML1), CAAT/enhancer-binding proteinUbiquitin-mediated protein degradation represents a critical mechanism in regulating the cellular levelsThus, targeting protein degradation has been emerging as an important strategy to conquer malignant diseasesIn this review, we will summarize the recent advances in the understanding of the roles of protein degradation

Keywords： protein degradation     leukemia     chemical biology     transcription factors     oncoprotein    

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Title Author Date Type Operation

Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Journal Article

Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction

Hong LI,Ziding ZHANG

Journal Article

Molecular simulation of the interaction mechanism between CodY protein and DNA in

Linchen Yuan, Hao Wu, Yue Zhao, Xiaoyu Qin, Yanni Li

Journal Article

Overlap maximum matching ratio (OMMR): a new measure to evaluate overlaps of essential modules

Xiao-xia ZHANG,Qiang-hua XIAO,Bin LI,Sai HU,Hui-jun XIONG,Bi-hai ZHAO

Journal Article

The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases

Yuan CHEN, Qi TIAN

Journal Article

Wheat gluten protein and its impacts on wheat processing quality

Wujun MA, Zitong YU, Maoyun SHE, Yun ZHAO, Shahidul ISLAM

Journal Article

Construction of sustainable, colored and multifunctional protein silk fabric using biomass riboflavin

Journal Article

Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:

Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang

Journal Article

Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology and protein

Baicheng HUANG, Kegong TIAN

Journal Article

Elevated C-reactive protein levels predict worsening prognosis in Chinese patients with first-onset stroke

Jiangtao YAN, Rutai HUI, Daowen WANG

Journal Article

Recombinant protein diannexin prevents preeclampsia-like symptoms in a pregnant mouse model via reducing

Journal Article

Investigation of hydrolysis conditions and properties on protein hydrolysates from flatfish skin

Hua ZHANG, Hongji ZHU, Shipeng WANG, Weihua WANG

Journal Article

Correlativity study between expression of DNA double-strand break repair protein and radiosensitivity

Liang ZHUANG, Shiying YU, Xiaoyuan HUANG, Yang CAO, Huihua XIONG

Journal Article

Protein phosphatase 2A, a key player in Alzheimer’s disease

Rong LIU, Qing TIAN

Journal Article

Molecular mechanisms of leukemia-associated protein degradation

Ying-Li WU, Guo-Qiang CHEN, Hu-Chen ZHOU,

Journal Article